Software

R Packages

• KnockoffHybrid: a knockoff framework for the identification of risk genetic variants in genome-wide association studies using hybrid analysis of both the trio and population designs. It implements the method in KnockoffHybrid: A knockoff framework for hybrid analysis of trio and population designs in genome-wide association studies.

• KnockoffTrio: a computationally efficient tool for the identification of causal loci in whole-genome sequencing family trio data. It also provides a meta-analysis module for combining the results of multiple studies. It implements the method in KnockoffTrio: A knockoff framework for the identification of putative causal variants in genome-wide association studies with trio design.

• HSVS-M: a Bayesian method for multi-variant multi-trait association testing using summary statistics. It implements the method in A Bayesian hierarchically structured prior for gene-based association test with multiple traits in genome-wide association studies.

• HSVS-A: a Bayesian method for rare-variant association testing. It implements the method in A Bayesian hierarchically structured prior for rare‐variant association testing.